Description
The EliSpot (Enzyme-linked immunosorbent Spot) assay measures the IFN-γ cytokine secretion associated with an active, chronic, or very recent infection. Read more
The Borrelia EliSpot includes 3 antigens:
- Borrelia burgdorferi Full Antigen: Borrelia burgdorferi B31-reference strain (Borrelia burgdorferi sensu stricto)
- Borrelia burgorferi Peptide-Mix: OspA from Borrelia b. sensu stricto, Borrelia afzelii, Borrelia garinii + OspC native + DbpA recombinant
- Borrelia burgdorferi LFA-1: Own body protein + Borrelia burgdorferi sensu stricto (shared epitope).
Often associated with autoimmune diseases: collagenosis, Rheumatoid Arthritis, vasculitis (ANA, CCP-antibodies, ANCA)
Explanation: OSP = Outer Surface Protein | Native = cultured antigens Recombinant: genetic technology produced | LFA = Lymphocyte Function Antigen