Description
Kryptopyrroluria (KPU), also known as hemopyrrollactamuria (HPU) or malvaria, is a metabolic disorder characterised by elevated levels of a chemical compound called pyrrole in the urine.
Pyrroles are substances formed during the breakdown of haemoglobin, which carries oxygen in red blood cells. In individuals with KPU, excessive levels of pyrroles are excreted in the urine, leading to deficiencies in essential nutrients like zinc, vitamin B6, and biotin.
This condition can manifest with a range of symptoms, and has been found to be an underlying factor in a vast range of conditions.