Description
The i-Spot (Enzyme-linked Immuno-Spot) assay measures:
IFN-γ cytokine secretion associated with an active, chronic, or very recent infection; and
IL2 secretion which represents the memory function of the immune system, and is associated with past infection.
About Varicella Zoster Virus (VZV)
The Varicella-Zoster Virus (VZV) is highly contagious and causes chickenpox (varicella) and shingles (herpes zoster). Transmission occurs mainly through droplets from infected individuals or through direct contact with skin lesions.
Chickenpox (Varicella): Chickenpox is the most common disease caused by the Varicella-Zoster Virus. It manifests as an itchy rash with blisters on the skin, accompanied by fever and general discomfort. The infection mostly affects children but can also occur in adults.
Shingles (Herpes Zoster): The Varicella-Zoster Virus can remain inactive (dormant) in nerve pathways and later reappear in life as shingles (Herpes Zoster). Shingles is characterized by a painful, itchy skin rash that extends on one side of the body or on the face.